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Fig. 8 | Molecular Medicine

Fig. 8

From: Differences in the Expression of Heat-Shock Proteins and Antioxidant Enzymes between Human and Rodent Pancreatic Islets: Implications for the Pathogenesis of Insulin-Dependent Diabetes Mellitus

Fig. 8

Effects of hydrogen peroxide, nicotinamide and nitroprusside on human islet GSH contents

GSH levels of dispersed human islet cells were determined as given in Fig. 6. Values are means ± SEM for two to three experiments, except with the 0.2 mM HP + 50 mM NA addition which represents only one observation. *p < 0.05 for a chance difference between control cells and cells incubated with 50 mM NA using Student’s paired t test. +p < 0.05 for a chance difference between 0.2 mM SP and 0.2 mM SP + 50 mM NA using Student’s paired t test. At all time points after Time 0, the 0.2 mM SP group was lower than controls (p < 0.05–0.01, Student’s paired t test).

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