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Table 1 Defective CCR5 allele in HIV-1 infected and uninfected children*

From: Prognostic Value of a CCR5 Defective Allele in Pediatric HIV-1 Infection

 

HIV-1 Uninfected Children

  

Origin

Exposed

Unexposed

HIV-1 Infected Children

Total

Italy

14+/172 (8.13%)

3/47 (6.38%)

20+/254 (7.87%)

37/473 (7.82%)

Spain

8/90 (8.88%)

n.d.

5/47 (10.64%)

13/137 (9.48%)

Total

22+/262 (8.39%)

3/47 (6.38%)

25+/301 (8.3%)

50/610 (8.19%)

  1. * Number of child carriers of the defective CCR5 allele out of total number of children tested. In parenthesis is the frequency of occurrence. Mean value of defective CCR5 allele of the HIV-1 uninfected children: in total 25/309 (8.09%), in Italy 17/219 (7.76%) and Spain 8/90 (8.88%). n.d. means not done.
  2. + Only one child of this group was a carrier of a homozygous deletion of the CCR5 gene.
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Molecular Medicine

ISSN: 1528-3658