Table 1 Effect of tolerization on physiologic parameters, immunoglobulin G (IgG) and immunoglobulin M (IgM) autoantibody titers assessed by ELISA, and cell populations assessed by FACS analysis (means ± SEM)

Weight (g)

33.4 ± 1.50

32.8 ± 1.30

25.3 ± 1.30

26.3 ± 0.90

Cholesterol (mmol/L)

1.58 ± 0.27

1.39 ± 0.27

1.30 ± 0.06

1.27 ± 0.30

ox-LDL

1.39 ± 0.06

1.32 ± 0.03

1.50 ± 0.08

1.51 ± 0.05

MDA-LDL

3.09 ± 0.16

2.78 ± 0.30

2.79 ± 0.21

2.69 ± 0.02

ox-LDL

1.11 ± 0.10

1.08 ± 0.05

1.19 ± 0.04

1.12 ± 0.02

MDA-LDL

2.30 ± 0.18

2.10 ± 0.26

2.87 ± 0.28

2.20 ± 0.49

CD19+

37 ± 2

40 ± 3

39 ± 2

41 ± 2

CD3 +

55 ± 2

52 ± 4

55 ± 2

53 ± 1

CD4+

52 ± 2

51 ± 2

45 ± 2

51 ± 2

CD8+

39 ± 2

40 ± 2

43 ± 2

37 ± 4

CD69+

4.7 ± 0.2

4.8 ± 0.5

4.0 ± 0.2

4.1 ± 0.8