Pattern of angiotensin I-converting enzyme (ACE) activity.
Activity in plasma (A) and homogenized tissues such as kidney (A), lung and testis (B), liver and spleen (C), brain and pituitary (D) from naive LEW/N and F344/N rats. ACE activity was measured against the synthetic substrate 3H-hippuryl-glycylglycine (3H-HGG) in 10 µl of plasma or diluted homogenized tissues (diluted 1:20 for lung and testis, 1:2 for other samples). Values of ACE activity were corrected by the total amount of protein (nmol/min/mg protein). Representative data are expressed as mean ± SD (n = 8). * = p <0.0001.