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Fig. 3 | Molecular Medicine

Fig. 3

From: Transfer Factors: Identification of Conserved Sequences in Transfer Factor Molecules

Fig. 3

Inhibition of expression of delayed-type hypersensitivity to Herpes simplex by LLYAQDLEDN.

Herpes simplex-glycoprotein D-specific transfer factors of either murine or bovine origin were given to BALB/cByJ mice (approximately 0.1 pMol per mouse). Other groups of mice received the same doses of the transfer factors and 0.1 µM of LLYAQDLEDN. Footpad testing was done as described. Significant (p < 0.001) footpad responses were observed in the transfer factor recipients. The recipients of both transfer factor and LLYAQDLEDN had footpad responses that were not different from the responses to HBSS. For the recipients of bovine Herpes simplex virus transfer factor (HSV-TF) the response to HBSS was 6.33 ± 1.52 × 102 mm and the response to HSV was 5.17 ± 0.83 × 102 mm (p > 0.50); the recipients of murine HSV-TF had responses to HBSS of 2.00 ± 1.33 × 102 mm and to HSV of 4.25 ± 2.13 × 102 mm (p > 0.30).

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