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Fig. 4 | Molecular Medicine

Fig. 4

From: Transfer Factors: Identification of Conserved Sequences in Transfer Factor Molecules

Fig. 4

Effect of LLYAQDLEDN on expression of delayed-type hypersensitivity by immunized mice.

Mice were sensitized to ferritin by immunization with ferritin in Freund’s complete adjuvant (FCA) and to Herpes simplex virus (HSV) by infection with sublethal doses of virulent human HSV-1. Treatment with LLYAQDLEDN did not inhibit expression of delayed-type hypersensitivity (DTH) in either group. For ferritin-immune mice the footpad response was 68.17 ± 11.66 × 102 mm; for ferritin-immune, LLYAQDLEDN-treated mice, footpad response was 75.00 ± 7.76 × 102 mm (p > 0.60). Mice that were sensitized to HSV by sublethal infection developed footpad responses to irradiated HSV of 24.80 ± 3.17 × 102 mm. The identically infected, LLYAQDLEDN-treated mice had footpad responses of 27.80 ± 3.98 × 102 mm (p > 0.50).

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