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Fig. 4 | Molecular Medicine

Fig. 4

From: Regulation of Laminin 1-Induced Pancreatic β-Cell Differentiation by α6 Integrin and α-Dystroglycan

Fig. 4

Number of β cells (open bar) and total cells (solid bar) after culture of 13.5-dpc fetal mouse pancreas cells for 4 days in presence of laminin-1 (200 µg/ml) and IIH6 blocking monoclonal IgM antibody to α-DG (A) or heparin (B), or in presence of laminin-1 (200 µg/ml) and heparin (100 µM) and indicated concentrations of GoH3 rat IgG2a monoclonal antibody to α6 integrin (C). β Cells were identified with guinea pig anti-insulin serum and peroxidase and cell counts were expressed at mean 6 SEM (n 5 3 separate experiments). *p, 0.005, **p, 0.01 versus in the presence of laminin-1 and IIH6 (A) or heparin (B).

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