Skip to main content

Table 4 Digenic analysis of α 1 Na,K-ATPase and Na,K,2Cl-cotransporter loci

From: α 1 Na,K-ATPase and Na,K,2Cl-Cotransporter/D3mit3 Loci Interact to Increase Susceptibility to Salt-Sensitive Hypertension in Dahl SHSD Rats

 

[R]

[S]

p Value

SBP ± SEM

151.3 ± 1.8

172.2 ± 4.7

5.85 × 10−6

DBP ± SEM

108.7 ± 1.6

125.5 ± 4.0

1.98 × 10−5

MAP ± SEM

128.9 ± 1.7

148.0 ± 4.3

7.73 × 10−6

n

35

12

 
  1. [R] genotypes: [RRNK+ RRNKC]; [RRNK+ SRNKC]; [RRNK+ SSNKC]; [SSNK+ RRNKC]; [SRNK+ RRNKC]; [S] genotype: [SSNK+ SSNKC]; NK: α1 Na,K-ATPase; NKC: Na,K,2Cl-cotransporter; SBP, systolic; DBP, diastolic; MAP, mean arterial blood pressures in mmHg; SEM, standard error of the mean; n, number of rats per group; p value, p value obtained in one-way ANOVA.