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Table 5 2 × 2 factorial ANOVA determination of α 1NK-NKC gene interaction

From: α 1 Na,K-ATPase and Na,K,2Cl-Cotransporter/D3mit3 Loci Interact to Increase Susceptibility to Salt-Sensitive Hypertension in Dahl SHSD Rats

Dependent Variable

Interaction Term (α1NK × NKC)

F

pValue

SBP

8.617

0.004

DBP

7.307

0.008

MAP

8.011

0.006

  1. Interaction term p value, 2 × 2 factorial ANOVA. The independent variables consisted of indicator variable values (e.g., R allele = 1; S allele = 2) assigned to each rat based on the genotypes for D2mgh11 (α1NK, factor 1) and for D3mit3 (NKC, factor 2) markers. 2 × 2 factorial analysis was done independently for SBP, DBP, and MAP.
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Molecular Medicine

ISSN: 1528-3658