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Fig. 1 | Molecular Medicine

Fig. 1

From: Role of Transcription Factor Nrf2 in the Induction of Hepatic Phase 2 and Antioxidative Enzymes in vivo by the Cancer Chemoprotective Agent, 3H-1, 2-Dithiole-3-thione

Fig. 1

Effect of nrf2 genotype and gender on hepatic activities of GST and NQO1 by D3T. GST (CDNB) and NQO1 (menadione) activities were measured in hepatic cytosols prepared from wild-type and nrf2-disrupted mice pretreated with D3T (0.3 mmol/kg p.o.) for 3 consecutive days. Mice were killed 24 hr after the last dose of D3T. (a) p, 0.05 compared to wild-type vehicle treated control. (b) p, 0.05 compared to wild-type mice treated with D3T. Values are mean 6 SEM for three animals in each group.

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Molecular Medicine

ISSN: 1528-3658