From: Role of Transcription Factor Nrf2 in the Induction of Hepatic Phase 2 and Antioxidative Enzymes in vivo by the Cancer Chemoprotective Agent, 3H-1, 2-Dithiole-3-thione
Genotype
+/+
−/−
Examples
O
↑
—
GST Ya, QR, mEH, yGCSr
U
T
GST Yp
C
↓
UGT1A6, HQ1, MnSOD
M
Ferritin H & L
E
GST Yc, AFAR, catalase
S
Albumin