Superposition of falcipain-1 and falcipain-2 model structures. A structural alignment of the falcipain-2 (red) and falcipain-1 (blue) model structures was performed with MINAREA (17). Structural positions present in falcipain-2 and absent in falcipain-1 are colored green. The catalytic dyad is shown in yellow for reference. The figure was generated with CHIMERA (18).