Fig. 2
From: The Impact of Whole Genome Sequence Data on Drug Discovery—A Malaria Case Study
The falcipain-2 model specificity sites. The residues that line the substrate specificity sites are displayed on the falcipain-2 model. The natural peptide substrate orientation prefers the non-prime side for the N-terminus, and the prime side for the C-terminus. Residues at the boundaries of a site may contribute to neighboring sites. The figure was generated with WEBMOL (20) and a sequence to structure alignment and family analysis JAVA™ package (M.P. Joachimiak, in preparation).