Fig. 1
From: Diabetes and the Role of Inositol-Containing Lipids in Insulin Signaling
Structure and hydrolysis of a GPI phospholipid by phospholipases D (PLD) and C (PLC) generating IPG type A and PA, and IPG-l,2-(cyclic phosphate) type A and DAG. Originally it was proposed that the responsible enzyme was a PLC, however, recent studies suggest that PLD is also capable of generating biologically active IPG type A from GPI (24,25). Ins, myo-inositol; GlcN, glucosamine; PA, phosphatidic acid; DAG, diacyl glycol.