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Fig. 5 | Molecular Medicine

Fig. 5

From: Developmental Expression of Wild-Type and Mutant Presenilin-1 in Hippocampal Neurons from Transgenic Mice: Evidence for Novel Species-Specific Properties of Human Presenilin-1

Fig. 5

Colocalization of PS1 with neuronal markers. Differentiated neurons were double labeled with a monoclonal antibody to microtubule-associated protein 2 (MAP2) (red) and with the PS1 C-terminal specific antibody 17.2 (green). The unique axonal distribution of the PS1 protein is indicated by the arrows (A). Similar cultures were double labeled with a monoclonal antibody to the growth cone marker GAP43 (red) and PS1 (green; antibody 17.2) indicating the overlap of staining within the extending processes and terminals (arrow) (B).

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Molecular Medicine

ISSN: 1528-3658