Fig. 4
Effects of leukotriene E4 on number of histamine Hj receptors in human peripheral blood monocytes. Blood was isolated from four healthy volunteers (A–D) and monocytes were prepared. The following day, monocytes were either left unstimulated (open circles) or stimulated with leukotriene E4 (100 ng/ml) (filled circles) for 15 min. Scatchard analysis was performed to determine number of receptors per cell as described in Materials and Methods.