Fig. 1From: Circular Antisense Oligonucleotides Inhibit Growth of Chronic Myeloid Leukemia CellsStructure of circular deoxy-nucleotides targeting K562 cell bcr-abl mRNA 385 nucleotides 5′ and 1735 nucleotides 3′ from the bcr-abl junction. Shown also is the method of synthesis of the former, including the target-like template oligonucleotide used to approximate the ends of the linear precursor.Back to article page