Skip to main content

Table 2 Correlation between NO-induced PBMC apoptosis and number of peripheral blood CD4 + cells in patients with AIDS

From: Critical Role of Nitric Oxide During the Apoptosis of Peripheral Blood Leukocytes from Patients with AIDS

PBMC from

Untreated

+ SNAPa

Apoptosisb (%)

P c

AIDS <300 CD4+ cells/mm3 (×10)

59 ± 12

34 ± 13

+43

<0.0001

AIDS >300 CD4+ cells/mm3 (×7)

56 ± 10

41 ± 13

+27

<0.005

Uninfected controls (×IO)

75 ± 8

60 ± 15

+20

<0.007

  1. aMean ± SD of percentage of cell survival following 4–6 days incubation of PBMC in medium alone or with 100 µM SNAP.
  2. bIncreased apoptosis in cells incubated with SNAP compared to cells incubated in medium alone.
  3. cSignificance of SNAP effect on cell survival.