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Table 4 Anti-donor and nonspecific cytotoxic activity of graft-infiltrating cells

From: RDP1258, a New Rationally Designed Immunosuppressive Peptide, Prolongs Allograft Survival in Rats: Analysis of Its Mechanism of Action

 

Donor cells (%)

YAC cells (%)

Untreated (n = 3)

22.8

15

RDP1258 treated (n = 3)

24

14

  1. Graft-infiltrating cells from treated and untreated recipients were tested for alloantigen-specific (donor cells) and nonspecific (YAC cell line) cytotoxicity. Data shown are the mean of triplicate determinations of 25:1 ratio, spontaneous release being <20% of maximum release in all experiments.
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Molecular Medicine

ISSN: 1528-3658