Fig. 1.From: Reactive Oxygen-induced Carcinogenesis Causes Hypermethylation of p16Ink4a and Activation of MAP KinaseGross view of nickel-sulfide induced sarcoma arising in a mouse. Limb assymetry in site of sarcoma (arrows) (1A), closeup of tumor (1B), and appearance of sarcoma under the skin (1C).Back to article page