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Fig. 4. | Molecular Medicine

Fig. 4.

From: Influenza Virus Infection is not Affected by Serum Amyloid P Component

Fig. 4.

Influenza infection in C57BL/6 SAP knockout mice and C57BL/6 SAP knockouts transgenic for human SAP. Body weight (left) and survival (right) following intra-nasal infection on day 0 with the A/PR/8/34 viral strain, in 23 female human SAP transgenic mice ( and solid line) aged 17–39 weeks, mean (SD) 29.0 (8.7) weeks, mean (SD) initial body weight 31.9 (3.7) g, and 23 female SAP knockout mice (□ and broken line) aged 17–39 weeks, mean (SD) 31.0 (6.3) weeks, mean (SD) initial body weight 30.6 (3.2) g. Each point (left) represents the mean (SD) of all surviving animals in each group at each time point. There was no significant difference in weight loss or survival between the groups.

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