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Fig. 3. | Molecular Medicine

Fig. 3.

From: The Dual AngII/AVP Receptor Gene N119S/C163R Variant Exhibits Sodium-Induced Dysfunction and Cosegregates With Salt-Sensitive Hypertension in the Dahl Salt-Sensitive Hypertensive Rat Model

Fig. 3.

Hormone-dependent stimulation of cAMP accumulation in Dahl S and Dahl R AngII/AVP receptors expressed in C127 cells. Ten micrograms of Dahl S and Dahl R AngII/AVP receptor expressing membranes were exposed to 0.1 µM of AVP (a) or 0.1 µM of AngII (b) at 25°C for 20 min in the presence of 0, 50, or 150 mM of NaCl, in comparison to basal control (no hormone added). Each experiment was performed in triplicate. Values are presented as mean ± standard deviation.

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