Plasma markers of thrombin production. Plasma TAT (A) and sGPV (B) levels in the three groups of rats. These two parameters of thrombin activation were correlated (C; r = 0.87, p < 0.0001). Plasma concentration of TAT was strongly correlated with the systolic BP in the l-NAME hypertensive rats (D; r = 0.72, p < 0.01). Values are means ± SEM. *p < 0.05 versus controls. $$p < 0.005 versus l-NAME.