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Fig. 5 | Molecular Medicine

Fig. 5

From: Temporal Morphogenesis of Herpes Simplex Virus Type 1-Infected and Brefeldin A-Treated Human Fibroblasts

Fig. 5

Ultrathin cryosections of HSV-1-infected and BFA-treated fibroblasts with BFA effects removed for 5 min (A) and 3 hr (B). The BFA clearly causes the capsids (arrows) to line up along reduplicated nuclear membranes intensely labeled with DL6 and GAR-G5 for gD-1 (A). Three hours after BFA removal (B), the nuclear membranes still contained gD-1 (arrows), but the capsids were moved from the nucleus to the gD-1-labeled endoplasmic reticulum. Bars: A–B = 0.25 µm.

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