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Table 1 Chemosensitization of MDA-MB-435/435 FF cells by AS HER-2

From: Tumor-targeting, Systemically Delivered Antisense HER-2 Chemosensitizes Human Breast Cancer Xenografts Irrespective of HER-2 Levels

AS HER-2 ODN Concentration

Lipofectin

F-Lip-2

0.1 µ M

0.3 µ M

0.1 µ M

0.3 µ M

Fold sensitization to paclitaxel

2.4

4.9

6.7

9

Fold sensitization to docetaxel

2.2

17

7.2

>30

  1. *Fold sensitization = ratio of IC50 for SC HER-2 ODN to IC50 for AS HER-2 ODN.
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