Table 2A Common sequence motifs A localized in TMS2 and TMS3 in the mycobacterial drug efflux transporters.
Predominant Residue at Position | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | |
Sequence | G | X | L | A | D | R | X | G | R | K | X | X | L |
Rv0037c | G | A | L | M | D | R | W | D | R | R | W | V | L |
Rv0191 | V | R | W | T | A | H | W | P | R | R | R | A | L |
Rv0783c | G | W | A | A | D | R | F | G | T | R | R | L | F |
Rv0849 | G | T | L | A | D | R | F | G | Y | K | P | L | I |
Rv1250 | G | R | L | G | D | R | F | G | P | K | N | L | Y |
Rv1258c | G | T | A | V | D | Y | F | G | R | R | R | V | S |
Rv1410c | G | R | A | S | D | R | F | G | R | K | L | M | L |
Rv1634 | N | T | M | L | L | R | V | G | A | R | S | S | Y |
Rv1877 | G | K | L | G | D | L | L | G | R | N | R | V | L |
Rv2333c | A | T | L | A | D | L | D | G | R | R | R | W | Y |
Rv2456c | G | A | L | V | D | R | T | T | A | K | R | A | L |
Rv2459 | A | L | L | G | D | R | Y | G | R | R | R | S | F |
Rv2846c | G | R | L | G | D | T | I | G | R | K | R | T | F |
Rv2994 | G | Y | L | L | D | H | V | G | E | R | M | V | M |
Rv3239c | G | R | L | A | D | L | L | G | R | R | R | T | F |
Rv3728 | G | R | L | A | D | L | M | G | R | K | R | V | F |
Consensus | G | R | L | [GA] | D | R | F | G | R | [RK] | R | V | [LF] |