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Fig. 5 | Molecular Medicine

Fig. 5

From: Adenoviral-Induced Islet Cell Cytotoxicity Is Not Counteracted by Bcl-2 Overexpression

Fig. 5

Effects of FCCP and Bcl-2 expression on JC-1 J-aggregate fluorescence in RINm5F cells (a) and islet cells (b). Cells were exposed for 24 hr to 5 µM of FCCP, followed by staining with 10 µM JC-1 and flow cytometry. Data are expressed as the 585/530 nm fluorescence ratio normalized to the reading of control (nontransduced, nontreated) cells. Results are mean ± SEM of six separate experiments. **p < 0.005 when comparing versus nontransduced and nontreated cells using one-way ANOVA, Bonferroni test. #p < 0.05, when comparing versus nontransduced cytokine-treated cells using one-way ANOVA, Bonferroni test.

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