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Fig. 3 | Molecular Medicine

Fig. 3

From: Islet Amyloid Development in a Mouse Strain Lacking Endogenous Islet Amyloid Polypeptide (IAPP) but Expressing Human IAPP

Fig. 3

(A) A pancreatic islet of a hIAPP+/+ mIAPP−/− male mouse, fed a high-fat diet for 9 months. Many scattered amyloid deposits are seen within the islet (yellow-red). Congo red in polarized light, examined with partially crossed polars. 200 × magnification. (B) Detail of a pancreatic islet of the same animal as in (A). Small extracellular amyloid deposits are evident. In addition, a cell, obviously filled with amyloid is seen. Congo red in polarized light, examined with partially crossed polars. 1000 × magnification.

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Molecular Medicine

ISSN: 1528-3658