Fig. 5From: Islet Amyloid Development in a Mouse Strain Lacking Endogenous Islet Amyloid Polypeptide (IAPP) but Expressing Human IAPPFibril formation of human islet amyloid polypeptide (IAPP) assayed by thioflavin T spectroscopy. Human IAPP spontaneously forms amyloid like fibrils whereas mouse IAPP does not. Mouse IAPP inhibits fibril formation of human IAPP in a dose-dependent manner.Back to article page