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Table 2 Compositional analysis of pancreatic islets in hIAPP+/+ mIAPP−/− mice and mIAPP−/− mice

From: Islet Amyloid Development in a Mouse Strain Lacking Endogenous Islet Amyloid Polypeptide (IAPP) but Expressing Human IAPP

 

Insulin

Glucagon

Somatostatin

Pancreatic Polypeptide

hIAPP+/+ mIAPP−/− mice (n = 5) male

67.2 ± 1.0

7.2 ± 0.3

4.9 ± 0.3

4.4 ± 0.9

mIAPP−/− mice (n = 5) male

65.6 ± 0.9

8.4 ± 0.6

6.4 ± 0.7

4.8 ± 1.0

hIAPP+/+ mIAPP−/− mice (n = 5) female

66.4 ± 1.2

7.6 ± 0.5

5.8 ± 0.4

3.2 ± 0.9

mIAPP−/− mice (n = 5) female

67.3 ± 0.9

7.8 ± 0.7

5.2 ± 0.8

3.6 ± 0.9

  1. Values are % of islet area.