Fig. 3From: Potent Induction of Apoptosis by β-Lapachone in Human Multiple Myeloma Cell Lines and Patient CellsInduction of DNA fragmentation by 0, 2, 4, 8 µM β-lapachone in human multiple myeloma (MM) cells. DNA laddering, a typical feature of apoptosis, was induced in: (A) ARH-77 treated with β-lapachone, (B) RPMI DOX-40, (C) MM.AS, (D) MM.1R. After exposure to the drug for 24 h, genomic DNA was extracted and subjected to agarose gel electrophoresis (19).Back to article page