Skip to main content
Fig. 5 | Molecular Medicine

Fig. 5

From: Tumor Necrosis Factor and Reactive Oxygen Species Cooperative Cytotoxicity Is Mediated via Inhibition of NF-κB

Fig. 5

H2O2 inhibits tumor necrosis factor alpha (TNFα)-induced nuclear translocation of NF-κB. (A) rat brain capillary endothelial cells untreated and those treated with (B) H2O2 or with (C) TNFα alone or with (D) both agonists for 30 min, were fixed and immunostained with anti-p65 antibody as described in Materials and Methods. Arrows denote accumulation of immunofluorescence in the nucleus in TNFα-treated cells (C) and in perinuclear area in cells treated with TNFα and H2O2 (D).

Back to article page

Molecular Medicine

ISSN: 1528-3658