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Table 2 Insulin and DNA content of islets isolated from Shb-transgenic mice

From: Transgenic Mice Expressing Shb Adaptor Protein under the Control of Rat Insulin Promoter Exhibit Altered Viability of Pancreatic Islet Cells

  Insulin Content (ng/10 islets) DNA (µg/10 islets) Insulin/DNA (ng/ng)
CBA 225 ± 21 0.17 ± 0.02 1.37 ± 0.11
Shb 340 ± 42* 0.26 ± 0.03* 1.36 ± 0.11
  1. Islets were isolated from control CBA mice and Shb-transgenic mice of both sexes and at age 3 months and maintained in tissue culture for 18 hr after which insulin content and DNA content were determined. Values are mean ± SEM for 7 to 9 observations.
  2. *p < 0.05 when compared with corresponding value of CBA control islets using an unpaired Student’s t-test.