Fig. 5From: Gene Expression Pattern in Human Monocytes as a Surrogate Marker for Systemic Inflammatory Response Syndrome (SIRS)Two models for induction of SIRS and progression to septic shock. (A) The SIRS definition describes a coherent pathophysiological state that may progress into shock. (B) SIRS describes a range of pathophysiological states that need not be mechanistically related. Each of these states may then progress to shock by a different route.Back to article page