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Fig. 4 | Molecular Medicine

Fig. 4

From: Butyrate Switches the Pattern of Chemokine Secretion by Intestinal Epithelial Cells through Histone Acetylation

Fig. 4

Effect of butyrate and IL-1β on IL-8 and MCP-1 mRNA accumulation in Caco-2 cells. Caco-2 cells were preincubated with butyrate (0, 2.5, 5 mM) for 24 hr and then stimulated with IL-1β (1 ng/ml) for 2 hr. IL-8 mRNA (upper panel) was increased by butyrate, whereas MCP-1 mRNA was decreased. These observations were quantified using densitometry (lower panel). The data are representative of three experiments.

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