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Table 2 Hormone levels in male Anx7(+/−) and control mice

From: Anx7 Is Required for Nutritional Control of Gene Expression in Mouse Pancreatic Islets of Langerhans

 

Glucagon (pg/ml)

IGF-1 (ng/ml)

GH (ng/ml)

Corticosterone (ng/ml)

Testosteron (ng/ml)

 

Anx7 (+/+)

 

Anx7 (+/−)

Anx7 (+/+)

 

Anx7 (+/−)

Anx7 (+/+)

 

Anx7 (+/−)

Anx7 (+/+)

 

Anx7 (+/−)

Anx7 (+/+)

 

Anx7 (+/−)

Average

48.61

 

56.31

288

 

287

0.93

 

0.82

266.07

 

193.38

0.54

 

0.66

SEM

3.06

 

4.86

23

 

9

0.14

 

0.11

49.41

 

24.22

0.1

 

0.2

n

4

 

4

2

 

26

21

 

20

14

 

13

6

 

4

p

 

>0.1

  

>0.1

  

>0.1

  

>0.1

  

>0.1

 
  1. Seven littermate pairs of male and female animals were used for these analyses. IGF-1 measurements were measured by a double antibody radio-immunoassay using recombinant human IGF-1 (Endocrine Sciences, San Diego, CA) and anti-human IGF-1 serum after removal of binding proteins from a 5 µl aliquot of serum using Sep-Pak C18 reverse phase cartridge (Millipore). Corticosterone was measured using 125I-corticosterone and anti-corticosterone antibody. Glucagon, growth hormone and testosterone were measured by radioimmunoassay using their respective antibodies.