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Table 3 Frequencies of the HLA class I specificities analyzed in selecting the putative CTL epitopes in the Gag protein (data from XII IHW)

From: Computer-Based Design of an HLA-Haplotype and HIV-Clade Independent Cytotoxic T-Lymphocyte (CTL) Assay for Monitoring HIV-Specific Immunity

HLA Specificity* Populations
Caucasian North African African Asian Amerind
A1 14.3 3.6 4.7 2.2 4.2
A2 27.8 13.6 16.9 25.1 31.5
A3 12.6 5.9 6.1 1.1 2.6
A24 8.9 5.4 3.4 24.3 18.0
A31 2.5 0.8 2.6 5.1 24.2
A33 1.7 8.0 8.2 7.8 5.1
A68 4.1 2.4 8.1 1.2 0
B7 9.2 4.2 7.4 8.6 2.7
B8 8.7 3.4 4.9 0.1 2.6
B14 3.7 3.6 2.8 0.4 3.2
B15 3.3 5.2 9.3 10.2 10.8
B27 3.8 1.7 1.2 1.8 1.0
B35 9.7 4.8 8.9 6.5 25.8
B37 1.4 0.8 0.7 0.7 0
B38 2.8 0.8 0.2 2.2 2.1
B39 1.9 4.5 1.2 3.6 17.9
B40 0.8 1.2 0.3 6.3 12
B44 12.1 5.1 5.8 5.4 2.2
B51 6.5 2.5 2.8 5.3 9.5
B52 1.6 2.5 2.7 5.8 2.4
B58 1.5 6.3 8.5 1.8 0.2
B60 3.4 0 0.4 4.4 1.5
B61 1.6 0.8 0.3 6.2 8.0
B62 4.7 1.8 0.8 9.2 5.3
Cw3 6.3 2.8 1.3 12.2 1.1
Cw4 12.3 11.8 16.5 5.7 18.9
Cw6 9.0 8.0 10.5 3.9 4.6
Cw7 23.3 13.7 17.4 17.0 30.6
Overall 96% 91% 93% 95% 98%
Specificity      
  1. *Data summarize the frequencies of the HLA class I alleles included in the serologic specificities reported and used for analyzing the putative CTL epitopes of GAG protein.
  2. †Overall frequency of the HLA class I haplotypes in the different populations including the serologic specificities analyzed.