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Table 2 [ 3 H] PK 11195 binding parameters (K d and B max ) on platelet membranes of controls and MD patients

From: Peripheral Benzodiazepine Binding Sites in Platelets of Patients Affected by Mitochondrial Diseases and Large Scale Mitochondrial DNA Rearrangements

  K d (nM) ± SEM B max (fmol/mg proteins) ± SEM
Controls (n = 15) 5.63 ± 0.46 4889.0 ± 357.8
Patients (n = 11) 13.18 ± 2.06* 2397.0 ± 305.6*
  1. Values were obtained by Scatchard analysis of saturation isotherms. Each value represents the means ± SEM of three separate experiments done on triplicate.
  2. *p < 0.05 versus controls.