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Fig. 2 | Molecular Medicine

Fig. 2

From: Farnesyl Protein Transferase Inhibition Interferes with Activation of MAP Kinase Family Members in Human Peripheral Blood Monocytes

Fig. 2

Effects of farnesyl protein transferase inhibition on JNK activation. FTIs inhibit phosphorylation of JNK after LPS stimulation in human peripheral blood monocytes. Cells were either incubated or not incubated with FTI (20 µM) for 16 hr and stimulated afterward with different concentrations of LPS (10 min). Phosphorylation of JNK was measured by Western blot in four volunteers. Antibody binding was quantified using image analysis software. All laboratory based values are given as means ± SEM.

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