From: Effects of Free Fatty Acid on Polymerization of Islet Amyloid Polypeptide (IAPP) In Vitro and on Amyloid Fibril Formation in Cultivated Isolated Islets of Transgenic Mice Overexpressing Human IAPP
Concentration of Fatty Acid* ( µ M)
500
50
0.5
0
IAPP alone
—
360
Myristic acid + IAPP
30
Oleic acid + IAPP
60
Palmitic acid + IAPP
Linoleic acid + IAPP
Stearic acid + IAPP