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Table 1 Time (min) after which amyloid-like fibrils appeared, as revealed by Congo red staining, when IAPP (50 µ M) and three different concentrations of fatty acids were co-incubated

From: Effects of Free Fatty Acid on Polymerization of Islet Amyloid Polypeptide (IAPP) In Vitro and on Amyloid Fibril Formation in Cultivated Isolated Islets of Transgenic Mice Overexpressing Human IAPP

     Concentration of Fatty Acid* ( µ M)
  500 50 0.5 0
IAPP alone 360
Myristic acid + IAPP 30 30 30  
Oleic acid + IAPP 30 30 60  
Palmitic acid + IAPP 30 30 30  
Linoleic acid + IAPP 30 30 360  
Stearic acid + IAPP 30 30 30  
  1. Results are from one out of three independent experiments, which all gave the same results.