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Fig. 2 | Molecular Medicine

Fig. 2

From: Human Breast Carcinoma Cells Express Type II IL-4 Receptors and Are Sensitive to Antitumor Activity of a Chimeric IL-4-Pseudomonas Exotoxin Fusion Protein in vitro and in vivo

Fig. 2

Displacement of 125I-IL-4 binding by IL4 and IL-4(38-37)-PE38KDEL. MCF-7 breast cancer cells were incubated at 4°C with 100 pM [125I]-IL-4 and various concentrations of either IL-4 or IL-4(38-37)-PE38KDEL. After 2 hr, cells were centrifuged through a mixture of phthalate oils and cell pellets were counted in a gamma counter. The data points shown are mean ± SD of duplicate determinations. A total of 1,491 ± 137 cpm bound to 1 × 106 MCF-7 cells. The SDs are shown where deviations are larger than the size of point symbols.

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Molecular Medicine

ISSN: 1528-3658