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Fig. 6 | Molecular Medicine

Fig. 6

From: Altered Expression of the Cell Cycle Regulatory Molecules pRb, p53 and MDM2 Exert a Synergetic Effect on Tumor Growth and Chromosomal Instability in Non-small Cell Lung Carcinomas (NSCLCs)

Fig. 6

Representative results of the multiplex reverse transcription polymerase chain reaction (RT-PCR) assay (see Methods) employed in order to evaluate the levels of MDM2 mRNA. m: 100bp DNA ladder; 1–2: Matched normal-tumor case (sample 8) with normal MDM2 mRNA expression; 3–4 and 5–6: Matched normal-tumor cases (sample 9 and 10, respectively) with MDM2 mRNA overexpression.

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