Fig. 1
From: In Vivo Analysis of DNase I Hypersensitive Sites in the Human CFTR Gene
Map of the region from −80 kb to −40 kb from the start of the CFTR gene (A) and of the region spanning the −20.5 and 185 + 10 kb DHS (B). (A) The extent of cosmids cJ21, phage R14.4, and plasmids pB14E4.9 and pB14E5.3 are shown (top). EcoRI sites (marked R) and fragments are also shown (middle). Fragments used as probes for mapping the 5′ end of the YAC are indicated by bold lines and type (not all data are shown), and distances 5′ of the ATG translation start site are indicated beneath the line. The −79.5 kb DHS is also indicated. The lower section shows HindIII sites and fragments above the line (marked H) and BamHI sites and fragments below it (marked B). The probable 5′ end of the YAC is indicated by an arrow below the line. (B) The extent of the cosmid cW44 is shown (top). The middle section shows HindIII sites (marked H), with HindIII fragments used as probes indicated by bold lines and labeled in bold type. The locations of the −20.5 kb and 185 + 10 kb DHS, and exon 1 are also shown. The position of the ATG translation start site and distances from it are indicated below the line. The lower section shows EcoRI sites (marked R) and sizes of EcoRI fragments above the line and BamHI sites (marked B) and fragments below it.