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Fig. 4 | Molecular Medicine

Fig. 4

From: Efficient Mitochondrial Import of Newly Synthesized Ornithine Transcarbamylase (OTC) and Correction of Secondary Metabolic Alterations in spfash Mice following Gene Therapy of OTC Deficiency

Fig. 4

OTC labeling in the cytosol of spfash/hOTC and spfash/mOTC hepatocytes. Ultrathin frozen liver sections from a spfash mouse treated with Ad.hOTC (A) and a spfash mouse treated with Ad.mOTC (B) were labeled by the rabbit anti-OTC antibody followed with gold conjugated goat anti-rabbit antisera. Arrows indicate OTC binding sites within the cytosol. ER, endoplasmic reticulum; N, nucleus. Bars, 0.1 µm.

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Molecular Medicine

ISSN: 1528-3658