Fig. 5
From: Loss of NF-κB Activity during Cerebral Ischemia and TNF Cytotoxicity
Overlap between anatomic areas of decreased NF-κB activity, apoptotic cell death, and TNF overexpression. Note that 24 hr after MCAO, the loss of NF-κB activity within the ischemic area (A, activity-specific anti-p65 antibodies) overlapped with profound apoptotic cell death (B, TUNEL) and significant up-regulation of TNF expression (C, monoclonal anti-TNF antibodies). The ischemic area occupies the right side of each figure (A–C).