Fig. 6
Distribution of PrPSc deposits in different brain areas. Relative amounts of PrPSc deposits in the cerebrum (cr), cerebellum (cl), and brain stem (bs) were determined by immunoblotting (A) and quantification through the photoimager technique (B). Relative percentages of cerebrum, cerebellum, and brain stem were calculated as arithmetic means ± standard error of the means of individual mouse homogenates. VM95 mice were inoculated with 87V (6 mice/24 gels); BSE-UK (4 mice/16 gels); BSE-G (4 mice/24 gels); and 22A (4 mice/19 gels). C57BL/6 mice were inoculated with 22A (4 mice/18 gels); Chandler (5 mice/31 gels); 79A (3 mice/12 gels); BSE-G (3 mice/26 gels); Hessenl (4 mice/19 gels); and S833 (4 mice/16 gels). Outbred CD-1 mice were inoculated with Chandler (6 mice/34 gels). Tg20 mice were inoculated with the Chandler strain (4 mice/16 gels) and Syrian hamsters (SH) were inoculated with 263K (4 hamsters/16 gels).