Skip to main content
Fig. 2 | Molecular Medicine

Fig. 2

From: IGF-I/IGFBP-3 Equilibrates Ratios of Pro- to Anti-inflammatory Cytokines, Which Are Predictors for Organ Function in Severely Burned Pediatric Patients

Fig. 2

(A) IL-6, IL-10, and IL-4 and their ratios. IGF-I/BP-3 decreased IL-6/IL-10 and IL-6/IL-4 and these ratios approached normal levels. Burn control patients demonstrated unchanged ratios of IL-6/IL-10 and IL-6/IL-4. *Significant difference between IGF-I/BP-3 and control at D 5 II (p < 0.05). Data are presented as means ± SEM. Normal values: IL-6/IL-10, 0.0005–0.0010; IL-6/IL-4, 0.00010–0.00025. (B) IL-6, IL-2 and IFN-γ and their ratios. IGF-I/BP-3 decreased IL-6/IL-2 and IL-6/IFN-γ when compared to controls. These ratios approached normal levels. Control patients had an increase or no change in these ratios. *Significant difference between IGF-I/BP-3 and control at D 5 II (p < 0.05). Data are presented as means ± SEM. Normal values: IL-6/IL-2, 0.0002–0.001; IL-6/IFN-γ, 0.0003–0.0010.

Back to article page

Molecular Medicine

ISSN: 1528-3658