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Table 2 Serum IGF-I and IGFBP-3, kidney and liver markers five days after the initiation of treatment or control

From: IGF-I/IGFBP-3 Equilibrates Ratios of Pro- to Anti-inflammatory Cytokines, Which Are Predictors for Organ Function in Severely Burned Pediatric Patients

  Control n = 7 IGF-I/BP-3 n = 17
  D 5 I D 5 II Δ (%) D 5 I D 5 II Δ(%)
IGF-I (µg/ml) 93 ± 9 103 ± 13 10 ± 7 102 ± 15 433 ± 33* 382 ± 44*
IGFBP-3 (µg/ml) 1.4 ± 0.2 1.6 ± 0.2 3 ± 8 1.5 ± 0.2 3.0 ± 0.2* 88 ± 12*
Creatinine (mg/dl) 3.3 ± 0.5 3.7 ± 0.8 5 ± 3 3.7 ± 0.4 2.3 ± 0.2* −20 ± 9*
Pre-albumin (mg/dl) 9 ± 1 11 ± 1 2 ± 7 11 ± 1 19 ± 1* 55 ± 9*
CHE (U/l) 840 ± 10 870 ± 15 3 ± 8 800 ± 15 2200 ± 30* 292 ± 40*
  1. Data presented as means ± SEM. Δ is defined as percent change from OP II to D 5 II.
  2. * Significant difference IGF-I/BP-3 vs. control (p < 0.05). ‡ Significant difference D 5 II vs. D 5 I (p < 0.05).
  3. Values for unburned normal children:
  4. IGF-I: 365 ± 15 µg/ml;
  5. IGFBP-3: 2.8 ± 0.9 µg/ml;
  6. Creatinine: 0.5–1.5 mg/dl
  7. Pre-albumin: 25–45 mg/dl
  8. CHE: 2400–8500 U/l.