Fig. 2

Intraperitoneal administration of recombinant ob protein into genetically obese mice

(A and B) Graphs showing the average weight gain in percentage over the weight at day zero of ob and db mice injected either with recombinant ob protein (solid line) or saline (dotted line). (C and D) Graphs showing weight gain in mg/day for the period of treatment and thereafter. The values were obtained by calculating the individual slopes for each animal from the experiments shown in Panels A and B.