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Fig. 2 | Molecular Medicine

Fig. 2

From: Molecular Cloning, Chromosomal Mapping, and Characterization of the Human Cardiac-Specific Homeobox Gene hCsx

Fig. 2

hCsx sequence comparison and schematic diagram

(A) Interspecies sequence comparison of the hCsx conserved domains. a, Homeodomain; b, TN-domain; c, NK2 domain. Dashes indicate amino acid identity with hCsx. The three helix motifs of the homeodomain are overlined. There is 100% identity between the murine Csx homeodomain and the hCsx homeodomain. In addition, the NK-2 and TN domains are completely conserved between the human, mouse, and Xenopus genes. (B) Schematic diagram of the hCsx cDNA. Entire boxed area indicates the coding region; thick lines, untranslated regions. The three hCsx subdomains are indicated in the figure. The probes used in the hybridizations and ribonuclease protection assays as well as the location of PCR primers are shown in the diagram (see text for details).

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